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March 15, 2024

Will weight loss drugs steal your all gains? | One Good Question

Will weight loss drugs steal your all gains? | One Good Question
Will weight loss drugs steal your all gains? | One Good Question
50% Facts with Silent Mike & Jim McD
Will weight loss drugs steal your all gains? | One Good Question

The exploding popularity of weight-loss drugs like Ozempic and Wegovy has raised awareness and demand for these “medical miracles” among the severely overweight…and the not-so-severely overweight.

Some questions have arisen about side effects – some...

The exploding popularity of weight-loss drugs like Ozempic and Wegovy has raised awareness and demand for these “medical miracles” among the severely overweight…and the not-so-severely overweight.

Some questions have arisen about side effects – some merely annoying and some potentially dangerous. One complaint is the loss of lean muscle mass. While this is obviously not ideal, is there something specific about these drugs that contributes to muscle loss, or is it nothing more than a normal effect of weight loss by any method? How can it be prevented?

Listener resources: Survey of studies on weight loss and muscle loss vs fat loss.

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Hosted by Mike Farr (@silentmikke) https://www.instagram.com/silentmikke/ and Jim McDonald (@thejimmcd). https://www.instagram.com/thejimmcd/ Produced by Jim McDonald Production assistance by Sam McDonald and Sebastian Brambila. Theme by Aaron Moore. Branding by Joseph Manzo (@jmanzo523).

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0:08 Ladies and gentlemen, Welcome to one good question, or one good topic, or whatever the hell we want to talk about on our Friday episode. Head over to three SB dot COO for all your apparel needs today. I think we're talking about drugs, drugs, weight loss drugs in particular. I was lessually listening to another podcast this morning and on the topic of weight loss drugs like ozepic and we go V and whatever, whatever whatever. And you know, a year ago, everyone, you know, not everyone, but a lot of people were like, Hey, these these drugs are great and there's like no side effect to them really at all, and really it's just all kind of all benefit and yeah and whatever, which just can't be true, which can't be true because there's I mean, it's impossible. Yeah, there's always there's always something. Yeah, there's always effects. Yeah, yeah, you get everything's fucking yeah. Great. When they say there's no such thing as a free lunch, they're not just talking about libertarianism. They're talking about about anything that you that you you're trying to alter yourself with. There's got to be every decision in life. Yeah, there's gonna be an effect.

1:15 Yeah, for sure, there's always there are always consequences. Yeah, but the one I mean there there are there are several that are being looked at right now that are potentially problems. One that does seem to be a thing is is slowing down how the stomach works, like maybe absorption itself. I mean, that's the concept of fat loss pills or weight loss pills in general, just by logic. And obviously there's many metrics and many different like channels they can go through to cause weight loss, but all of them are affecting probably what you absorb, and so you're probably gonna have some kind of health issue. Yeah. And then like you're not gett enough vitamins, you're not get enough minerals, maybe the protein synthesis is affected, who knows. Yeah, And then it's always just to what extent, like how fatten out of shape and unhealthy are you? And is this worse or better? Yeah?

2:10 Yeah? Are you? Are you improving your your outcomes enough? Yeah, which is probably true if you're very unhealthy. But with those zepic in particular, it's gotten so popular because it does work so well that it's being like over the counter used, It's being used left and right. Yeah, by like just folks. Yeah, and if you're like semi healthy and just want to get shredded, now, those negatives that may come from any pill, not even just this one, are probably not worth it, right, But if you're on the edge of death and you're eight hundred pounds and your type two and your blood pressure and all this, then you know it might be worth a little writ more more of a stronger attack. Yeah, like more, more in that vain. Previous guests on this show doctor Spencer and the Nadelski is a proponent of these of these drugs, and he points out that he's been called a shill for Big Farm or whatever for doing this, but like his point is that people who are are are desperate the you know, the the end justify the means. Yeah, yeah, Yeah, it's obviously per person. And the issue with someone like Nadolski is that he's an online presence, so things can get clipped out of context, taken out of context.

3:23 Yeah, he only has one hundred and forty words to get across what he's trying to say. Yeah, and then people are gonna take what they want, Like, I'm sure we could talk to him and he's not gonna say like I should take it right now to drop my last five pounds. A. Yeah, because that doesn't actually make any sense. You you you, I mean, you probably wouldn't qualify for just just on that on that basis, unless you were, like, I don't know, borderline diabetic or something. Yeah, I don't think qualifications matter. Yeah, I don't think they. I don't think they do either because of the way people are getting right, you're getting it, you get, you get. It's not directly over the counterbit it practically is because you're not mostly not dealing with a real doctor. Every minute you know, you're you're checking in with a with a doctor, and you know they're probably motivated to continue selling it because they're making money. Well, not even just in America. It doesn't matter if it's over the counter or not. You can get whatever you want. Yeah, this is true. People joke about Mexico making everything legal, but like, if you want something in America, you can go get it. You pretty much go get it. The An interesting thing about about doctor Nadolski, though, is he is now the medical director of Weight Watchers, and weight Watchers has always been anti diet drug. Did Oprah hop out of that thing Oprah left the board. Yeah, and and the reason that was given was that she was using one of one of these drugs and didn't want to, you know, be the one setting the exam. You know, an example that goes against what supposedly the the philosophy of the company. But on the other

4:55 hand, doctor Nadelski is someone who is a proponent of it. So I don't know. It feels like maybe there was another reason, or she just has personal she has personal feelings about about the message, it, sentence or whatever. Yeah, who knows? Who? Yeah, who knows? This is really quick. It's such a big business when you're starting to deal with in those realms. Who knows what's going on? Correct? Yes, the more the more digits to the left of the decimal point, the more complicated thing. Sure, sure so, in particular for like our world, the question is about muscle loss. How you know, people talk about ozembic face or Ozmpic butt. I haven't heard of ozmpic butt. Yeah. Basically yeah, flat yeah, yeah, No one likes is the fact. I swear to God when in the nineties a flat ass was hot though maybe now for sure, like you look at all the models and stuff in the nineties and they're all like stick thin. Yeah, you're super thin. Yeah. No, Like maybe titties were hot, like they just started to become like a thing to give fake tits, like the Pam Anderson's and Carmen and Electras.

6:04 But like all the sexy chicks on the commercials and whatever, he had like no ass, and now everyone's got a fake ass. Everyone has to fake ass. Yeah, that's it. The revolution is the fake ass. I mean it's you know, there's no in between. It's boobs on your butt, you know. Yeah, yeah, yeah, every rapper's got a fucking crazy surgery. Ass surgery. It's just so crazy. That's only twenty years difference to go from not only the extremes, but what all society in the Western world considers. Yeah, roughly. Obviously, everyone's got their own personal preference. You can like flat asses for all I care. I don't give a fuck what you like. But generally the society and the culture is now.

6:48 Yeah, just talk about one eighty holy shit pum swinging. Yeah yeah, and the whole like valuing an ass and the thigh gap at the same time. Yeah, yes, I got it. Yeah, in our world is faux pa. But in general, people still dig it, and then hip dips are a thing people talk about, but that's like genetic, I mean, all of its kind of genetic. I don't know. Man, it's hard to be a dude in the fitness space, but it's probably really hard to be a chick. I imagine it's very challenging yeh, yeah, to meet expectations. But anyway, I will I will link some studies into this. But talking about muscle mass loss, apparently studies are showing that the muscle mass loss is about the same as losing weight period. Yeah. Part of the issue probably is, yeah, again, who they're testing. If they're testing people that actually qualify for the drug, then chances are they might not be eating adequate protein to begin with. Yeah, they're probably not resistance training to begin with. They're probably not very athletic and fit to begin with.

7:50 So then, like not to say the studies don't matter, but it almost controls that variable quickly, right, It controls a variable. Have no mo ustle, get no muscle, yeah exactly. Yeah, if you're if you're peeling stuff off, and if you particularly if you're losing muscle and fat in the same proportion, you know, fifty to fifty ish whatever. Yeah, at that point it just doesn't matter really because yeah, if you're eight hundred pounds, we just got to get some weight off you, so you're fucking pipes can work a little better. But then once yeah, once you start to get into the casual user of it, right, that's yeah, may or may not matter, or or or you know, again, it may have different effects depending on the age group, depending on how active they are. If they're if the studies on a bunch of people that are like extreme obese and have no activity, they're losing no muscle, maybe because they got no muscle to lose. Yeah, right, if we do it on more of a moderate crowd and we hit some fifty year olds that are just a little bit overweight and still qualify for this, maybe they are type two or something. Are they losing muscle at rates that may be unhealthy? Or bone I know, bone density in intensity is an issue that's still being studied.

9:00 Yeah, that's always been a thing with diet drugs and dieting in general, and diabetes obviously, absorption of vitamins and minerals with all these drugs, because even in my time in the fitness industry. Like, I've paid attention to the shit since maybe two thousand and six closely, and before that was just you know, magazines or whatever. Beef had magazines, but uh, there's never been a drug that people like were like kind of about. Yeah. Most of them were sugar pills, you know, or they're so extreme they just didn't work. Like to have an actual diet pill that may help, but again, like it doesn't really help, right because then when you get off it, what's gonna happen. Have you changed your habits, have you exercised, do you know how to eat? Do you understand anything about nutrition? Are you still going back to your big gulp of you know, one hundred and eighty grams of sugar every gas station. So, like the root cause may not be an issue or may still be an issue. Yeah, for sure. And just like with regular dieting, like it's not if you're trying to lose weight, it's not really acquired that you lift weights, do resistance training, get exercise whatever. It's just so much better for your body in the end, and a way to deal with with potential muscle loss and any kind of of fat loss scenario is resistance training. Yeah, I mean that's the habit part, right, Yeah, what are you trying to be healthy and move? And as you get older and you fall and you bump shit, do you want muscle and bone to be ready for it?

10:24 And the only way to get continue that is resistance training. You know, milk can diet, it doesn't really have a ton to do with it. Enough protein to list some weights is a way to kind of help all your bones and all your muscles. But it should go in phases. And that's the issue if you're calling someone like a pharmaceutical shill, Like how many doctors are like paid by the round or by the point of what they're doing, and so they're seeing someone for five minutes because they're checking off their list, they go on the next person, the next person, rather than if you have someone who's type two and all this stuff and they're trying to change them, you know, they need like real consulting and like habit changes, life changes. Yeah, Mozimbic would be great to kick start that. Yeah, you know, so they're not slamming mcflurries at midnight every night, and maybe they're not as hungry, But then if they're not learning anything about healthy lifestyle or an active lifestyle, then now we're just kind of yeah, they're popping steroids and the dead chicken. Yeah. The the recommendation obviously is to have diet, you know, the nutrition, counseling and sure all of that stuff and len therapy for a lot of people just straight up talk therapy and stuff along with these drugs and not to take them by themselves. But that's also true of like any depression drugs, and they get prescribed all the time without the without the talk therapy component. When you talk about the reality of all this, like say someone is extreme overweight, you can't even hold a job,

11:56 how are they going to afford the pill doctor, visits nutrition, personal trainer. I mean, that's the only way it's going to work. Chances that you just all of a sudden become so motivated and grab all the information on Google, start working out by yourself three times a week, start eating perfectly, and taking ozepic without any professional help is probably slimmed to none. And then the fact that you're in this situation to begin with and you can afford the time and the money to do grab all these professionals probably also slim to none. You know, I've never heard or seen that type of transformation just because it's so hard people have done on their own, for sure, and I've got people like that that something did flip and they have fixed it.

12:39 But that's one in a billion. And then yeah, it's just it's just such a complicated issue, starting with education and just generally how our whole society's built up. Sadly, Yeah, for sure. So well, this is not a medical show. We are, but don't take ozepic, you fatties. Go figure it out. Or if you do, do it the right way. That's yeah, go lift some weight. That's true about dieting period. Do it the right way. You need to start lifting waste, do it the right way. Yeah, go lift weights, Go lift weights. It fixes a lot of things. Ladies and gentlemen. New episode Wednesday and Friday. If you're in California this weekend, we got to meet starting at nine am both Saturday and Sunday. Come hang out. Spectators allowed, twenty bucks. We'll be kicking it all weekend long thursd Street, bar Bell, Sacramento, California. If you looking for a gym in a community, come get better and actually get fit. We don't sell o zembic andsp dot CF for all your clothing needs. I'm sorry, like w are you want find me? I am at the Jim mcdehan all the social media. This show is fifty percent facts, for percent is a word and fifty is just numbers. Fifty percent facts. This is a Spreaker Prime podcast in association with our Heart Media on the Obscure Celebrity Network and We'll talk to you next time.